Hi Dipak,
You have to check the flag as "Local", If EM installed in same server and same client. If it is different client and different system, then uncheck the flag.
If you are working on Dev and QA servers then "Sync" should be checked and Production system "Sync" should be unchecked.
1. Event Management Interface -> Define System Configuration -> Define RFC Connection to SAP EM ->Click ABAP connection -> create - this always done by SAP BASIS team that you have to ask them to create one.
2. Event Management Interface -> Define System Configuration -> Define Logical System here
3. Event Management Interface -> Define SAP EM -> Here need to enter Local or Non-Local.
Regards
GGOPII